In the case of narcolepsy, the insufficient amount of orexin is a result of a faulty autoimmune response. This neuropeptide is involved in regulating sleep-wake cycles in humans, as well as feeding behaviors. The main known cause for narcolepsy is the lack of hypocretin, also known as orexin, which is a brain chemical. This should not be mistaken with occasions where one might nod off while watching a movie – in the case of narcolepsy the individual might collapse (due to falling asleep) while standing up, in mid-sentence or while making a presentation. This means an individual suffering from narcolepsy can fall asleep unexpectedly, at any time. Narcolepsy is defined as a long-term brain condition that manifests through the inability to regulate sleep-wake cycles appropriately. The registry is voluntary, and individuals can opt out of it at any time. Upon a diagnosis of narcolepsy, and with consent of the individual, the information is submitted to National Congenital Anomaly and Rare Disease Registration Service (NCARDRS) in the US, which helps clinicians and scientists to search for ways of treating, preventing, and diagnosing narcolepsy. There are support groups available for individuals suffering from narcolepsy, which can provide support and a safe environment for sharing your experience.
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